The Drop Shape Analyzer – DSA25 is a reliable instrument for measuring contact angle. From a simple wetting test to the accurate measurement of surface free energy, the instrument provides flexible options for analyzing wetting and adhesion on solid surfaces. Its rapid, manual operation makes the DSA25 suitable for occasional wetting measurements with changing tasks and sample types.
Surface plasmon resonance
Surface Plasmon Resonance (SPR) is an established method for biomolecular interaction analysis. It is popular due to its sensitivity and its real-time label-free principle. Multi-Parametric Surface Plasmon Resonance (MP-SPR) is based on SPR theory, however its advantageous optical setup measures a full SPR curve which enables new insight into interactions. MP-SPR widens the application range of traditional SPR from small molecules up to nanoparticles and even living cells. Measurements can be performed even in complex media such as serum.
MP-SPR uniquely provides also information about layer properties. Thickness and refractive index data can be utilized in material characterization from Ångström thick layers up to micrometers or to ensure conformation of the molecules on the surface.
Quartz crystal microbalance
Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D) enables real-time analysis of surface-molecule interactions with nanogram precision for a wide variety of samples and measurement conditions. A QCM-D instrument measures the combined mass of the adsorbing material and the solvent coupled within the structure, the so-called wet mass. It also detects structural changes within the adsorbed film. The combination of the two techniques therefore enables quantification of solvent content in the film and can also strictly distinguish between structural changes caused by solvent uptake/release or conformation changes such as cross-linking.